Direct Allergy understands the concerns of physicians considering adding allergy testing and treatment to their practice.
Allergy testing and Immunotherapy have been around since 1911 and have benefited many patients since their discovery. Direct Allergy utilizes the Modified Quantitative Testing (MQT) Protocol, which blends skin-prick and Intradermal Testing (IDT) into a single, simple, safe testing method . Direct Allergy brings almost 40 years of clinical expertise and oversight to the field of allergy testing and treatment.
A report from the Mayo Clinic on 79,593 Immunotherapy injections over a 10-year period showed the incidence of adverse reactions to be less than two-tenths of one percent (0.137 percent). Most of the reactions were mild and responded to immediate medical treatment. There were no fatalities . More than one million injections were given without a fatality to 8,706 patients in allergy clinics at Roosevelt Hospital in New York City between 1935 and 1955 .
Rare occurrences of fatal anaphylactic episodes related to Immunotherapy are reported and studied. A total of 35 deaths following Immunotherapy administration were reported for the years 1985 through 1993. It has been estimated that during that period there were 52.3 million Immunotherapy procedures, making the incidence of fatality less than one per million (0.6692 per million) . Data recently compiled by the Allergen Products Manufacturers Association (APMA) estimated the incidence of fatalities to be about three per 190 million annual injections, or approximately one per 63 million injections .
Another study evaluating 13 international fatalities related to Immunotherapy between 1992 and 1996 identified an elevated risk for patients with active asthma who are being switched to high doses . For perspective, it is useful to compare these statistics with the incidence of fatalities related to other kinds of injections. Studies of fatal anaphylaxis reactions to injected penicillin have ranged from 0.4 fatalities per million injections  to one fatality per 7.5 million injections . Fatalities related to radiocontrast “dyes” used in intravascular radiologic studies in the early 1980s varied from one in 13,000 procedures  to one in 75,000 procedures . A more recent study showed a substantial improvement to about one fatality in 169,000 procedures .
Many of the antigen manufacturers have a large number of clients who are primary care physicians, and they’ve organized medical societies dedicated solely to the training of primary care physicians in the field of allergy. The key to safety is training and oversight.
Direct Allergy provides physician and nurse training through its national nurse trainer. The nurses go through comprehensive training protocol. Periodic reviews are conducted by Direct Allergy’s nurse trainer. Utilizing the MQT testing protocol, combined with a safety test for each vial, the potential for adverse reactions is greatly diminished. The nurses are highly trained to be aware of patients who may not be suitable candidates for testing and treatment. Direct Allergy clients always have access to clinical oversight should the need arise. We provide a partnership that helps you safely manage the allergy patients in your practice.
 Quantitative Skin Testing for Allergy : IDT and MQT, Marple and Mabry, August 2006
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 Data on file with the Allergen Products Manufacturers Association. April 1997 Communication.
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